Bioinformatics, which can be defined as the application of computer science and information technology to the field of biology and medicine, has been rapidly developing over the past few decades. It generates new knowledge as well as the computational tools to create that knowledge. Understanding the basic processes in living organisms is therefore indispensable for bioinformaticians. This book addresses beginners in molecular biology, especially computer scientists who would like to work as bioinformaticians. It presents basic processes in living organisms in a condensed manner. Additionally, principles of several high-throughput technologies in molecular biology, which need the assistance of bioinformaticians, are explained from a biological point of view. It is structured in the following 9 chapters: cells and viruses; protein structure and function; nucleic acids; DNA replication, mutations, and repair; transcription and posttranscriptional processes; synthesis and posttranslational modifications of proteins; cell division; cell signaling pathways; and high-throughput technologies in molecular biology.
生物信息学可以定义为将计算机科学和信息技术应用于生物和医学领域，近几十年来得到了快速发展。它不仅产生了新的知识，还创造了计算工具来创造这些知识。因此，了解生物体内的基本过程对于生物信息学家来说是不可或缺的。本书主要面向分子生物学的初学者，特别是希望成为生物信息学家的计算机科学家。它以简洁的方式介绍了生物体内的基本过程。此外，从生物学角度解释了几种需要生物信息学家协助的分子生物学高通量技术的原理。本书分为以下9章：细胞和病毒；蛋白质结构和功能；核酸；DNA复制、突变和修复；转录和转录后过程；蛋白质合成和翻译后修饰；细胞分裂；细胞信号通路；以及分子生物学高通量技术。