Thoroughly updated to reflect major advances in the field of immuno-oncology, this second edition of Cancer Immunotherapy Principles and Practice, from the Society for Immunotherapy of Cancer (SITC), remains the definitive resource for information on tumor immunology and cancer immunotherapy treatments. An essential reference for both novice and experienced cancer researchers, oncologists, and related practitioners alike, the book not only guides readers through the fundamental scientific principles of the field all the way to translational and practical clinical applications for treating and managing oncologic disease, but also provides a comprehensive understanding of the regulatory processes that support the safe and effective delivery of immunotherapy to patients with cancer.
经过全面更新以反映免疫肿瘤学领域的重大进展，这本来自癌症免疫治疗学会（SITC）的《癌症免疫治疗原理与实践》第二版仍然是关于肿瘤免疫学和癌症免疫治疗治疗信息的权威资源。对于初学者和有经验的癌症研究人员、肿瘤学家和相关从业人员来说，这本书不仅引导读者了解该领域的基本科学原理，一直到治疗和管理肿瘤疾病的转化和实际临床应用，而且还提供了全面的了解支持将免疫治疗安全有效地应用于癌症患者的监管过程。
The expanded and updated second edition now spans 68 chapters, including 12 new chapters, covering major topics and innovations that have shaped the rapid development of immunotherapy and its ascension into the standard of care as first-line treatment for a growing number of disease settings. New to this edition are chapters with deeper insight into our understanding of cancer genomics and determinants of response, immunogenic cell death, cancer and stromal cell-intrinsic pathways of immune resistance, cancer immune exclusion, adoptive cell therapy, metabolomics, tumor mutation burden, immunotherapy in combination with radiation therapy, synthetic biology, and more. Complete with detailed illustrations, tables, and key points for targeted reference, Cancer Immunotherapy Principles and Practice, Second Edition is the most comprehensive and authoritative resource for scientists and clinicians looking to expand their knowledge base of this dynamic field.
经过扩展和更新的第二版现在涵盖了68个章节，其中包括12个新章节，涵盖了主要主题和创新，这些主题和创新塑造了免疫治疗的快速发展，并将其提升为越来越多疾病治疗的一线治疗标准。本版新增了更深入的章节，涉及我们对癌症基因组学和反应决定因素、免疫原性细胞死亡、癌症和基质细胞内在的免疫耐药通路、癌症免疫排斥、细胞免疫治疗、代谢组学、肿瘤突变负荷、放射治疗联合免疫治疗、合成生物学等方面的理解。配有详细的插图、表格和重点内容，是科学家和临床医生扩展其动态领域知识库的最全面和权威的资源。
Key Features:
Offers key insights and perspectives on cancer immunology and immunotherapy treatments from renowned experts in the field
从该领域的知名专家那里提供癌症免疫学和免疫治疗治疗的关键见解和观点
Covers the basic principles and science behind cancer immunotherapy and tumor immunology
涵盖了癌症免疫治疗和肿瘤免疫学的基本原理和科学
Includes treatment strategies for a vast array of available immunotherapy classes and agents, such as cytokine therapies, oncolytic viruses, cancer vaccines, CAR T therapies, and combination immunotherapies
包括针对广泛的免疫治疗类别和药物的治疗策略，例如细胞因子疗法、溶瘤病毒、癌症疫苗、CAR T疗法和联合免疫疗法
Provides essential information on FDA-approved immunotherapies, including clinical management and outcome data related to response rates, risks, and toxicities
提供关于FDA批准的免疫疗法的基本信息，包括与响应率、风险和毒性相关的临床管理和结果数据
Discusses special considerations for immunotherapy in the context of specific disease settings, including skin cancers, genitourinary cancers, gastrointestinal cancers, hepatocellular carcinomas, gynecologic malignancies, breast cancers, lung cancers, head and neck cancers, brain tumors, sarcomas, pediatric cancers, and treatments combined with radiation therapy
讨论了在特定疾病情境下免疫疗法的特殊考虑因素，包括皮肤癌、泌尿系统肿瘤、胃肠道肿瘤、肝细胞癌、妇科恶性肿瘤、乳腺癌、肺癌、头颈部肿瘤、脑肿瘤、肉瘤、儿童肿瘤以及与放疗联合治疗的情况
Clarifies the complex regulatory aspects behind the development and approval of immunotherapy drugs
阐明了免疫治疗药物开发和批准背后的复杂监管方面
Purchase includes access to the eBook for use on most mobile devices or computers
Description:
Thoroughly updated to reflect major advances in the field of immuno-oncology, this second edition of Cancer Immunotherapy Principles and Practice, from the Society for Immunotherapy of Cancer (SITC), remains the definitive resource for information on tumor immunology and cancer immunotherapy treatments. An essential reference for both novice and experienced cancer researchers, oncologists, and related practitioners alike, the book not only guides readers through the fundamental scientific principles of the field all the way to translational and practical clinical applications for treating and managing oncologic disease, but also provides a comprehensive understanding of the regulatory processes that support the safe and effective delivery of immunotherapy to patients with cancer. 经过全面更新以反映免疫肿瘤学领域的重大进展，这本来自癌症免疫治疗学会（SITC）的《癌症免疫治疗原理与实践》第二版仍然是关于肿瘤免疫学和癌症免疫治疗治疗信息的权威资源。对于初学者和有经验的癌症研究人员、肿瘤学家和相关从业人员来说，这本书不仅引导读者了解该领域的基本科学原理，一直到治疗和管理肿瘤疾病的转化和实际临床应用，而且还提供了全面的了解支持将免疫治疗安全有效地应用于癌症患者的监管过程。 The expanded and updated second edition now spans 68 chapters, including 12 new chapters, covering major topics and innovations that have shaped the rapid development of immunotherapy and its ascension into the standard of care as first-line treatment for a growing number of disease settings. New to this edition are chapters with deeper insight into our understanding of cancer genomics and determinants of response, immunogenic cell death, cancer and stromal cell-intrinsic pathways of immune resistance, cancer immune exclusion, adoptive cell therapy, metabolomics, tumor mutation burden, immunotherapy in combination with radiation therapy, synthetic biology, and more. Complete with detailed illustrations, tables, and key points for targeted reference, Cancer Immunotherapy Principles and Practice, Second Edition is the most comprehensive and authoritative resource for scientists and clinicians looking to expand their knowledge base of this dynamic field. 经过扩展和更新的第二版现在涵盖了68个章节，其中包括12个新章节，涵盖了主要主题和创新，这些主题和创新塑造了免疫治疗的快速发展，并将其提升为越来越多疾病治疗的一线治疗标准。本版新增了更深入的章节，涉及我们对癌症基因组学和反应决定因素、免疫原性细胞死亡、癌症和基质细胞内在的免疫耐药通路、癌症免疫排斥、细胞免疫治疗、代谢组学、肿瘤突变负荷、放射治疗联合免疫治疗、合成生物学等方面的理解。配有详细的插图、表格和重点内容，是科学家和临床医生扩展其动态领域知识库的最全面和权威的资源。 Key Features: Offers key insights and perspectives on cancer immunology and immunotherapy treatments from renowned experts in the field 从该领域的知名专家那里提供癌症免疫学和免疫治疗治疗的关键见解和观点 Covers the basic principles and science behind cancer immunotherapy and tumor immunology 涵盖了癌症免疫治疗和肿瘤免疫学的基本原理和科学 Includes treatment strategies for a vast array of available immunotherapy classes and agents, such as cytokine therapies, oncolytic viruses, cancer vaccines, CAR T therapies, and combination immunotherapies 包括针对广泛的免疫治疗类别和药物的治疗策略，例如细胞因子疗法、溶瘤病毒、癌症疫苗、CAR T疗法和联合免疫疗法 Provides essential information on FDA-approved immunotherapies, including clinical management and outcome data related to response rates, risks, and toxicities 提供关于FDA批准的免疫疗法的基本信息，包括与响应率、风险和毒性相关的临床管理和结果数据 Discusses special considerations for immunotherapy in the context of specific disease settings, including skin cancers, genitourinary cancers, gastrointestinal cancers, hepatocellular carcinomas, gynecologic malignancies, breast cancers, lung cancers, head and neck cancers, brain tumors, sarcomas, pediatric cancers, and treatments combined with radiation therapy 讨论了在特定疾病情境下免疫疗法的特殊考虑因素，包括皮肤癌、泌尿系统肿瘤、胃肠道肿瘤、肝细胞癌、妇科恶性肿瘤、乳腺癌、肺癌、头颈部肿瘤、脑肿瘤、肉瘤、儿童肿瘤以及与放疗联合治疗的情况 Clarifies the complex regulatory aspects behind the development and approval of immunotherapy drugs 阐明了免疫治疗药物开发和批准背后的复杂监管方面 Purchase includes access to the eBook for use on most mobile devices or computers